Esh Group Eagles Newcastle pulled away from Cheshire Phoenix to record an 85-99 road victory, on Sunday evening.
Scott Martin led the way with a 28-point haul to help his team get off to a winning start as all nine players got onto the scoresheet.
After a tightly contested first period, the Eagles began to edge away, putting together a 16-2 run across quarters to lead by 12 at 22-34. Cheshire scored seven straight either side of half-time to close within three, but would not get closer.
Defoe scored six points in a 13-2 run as Newcastle re-gained a double-digit advantage and a further 10-1 burst in the fourth would make sure of the result with the visitors ahead by as many as 21 with three minutes to go.